Dermamelan Depigmentation

Skin ageing caused by systematic sun exposure, facial blemishes due to excessive pigmentation and, in general, imperfections caused by melanin, are more and more common problems today…“Dark blemishes”, especially on hands and face, are one of the greatest aesthetic concerns of modern men and women… It will only be possible to remove the anti-aesthetic skin blemishes and recover the smoothness of the skin, bringing back its luminosity, with a treatment that has a direct effect on the intimate formation process of the pigment (melanin).

When would one use Dermamelan?
Dermamelan, for doctor’s use only, is used for severe pigmentation.
At Clínica Privé, to improve results with Dermamelan, a Mesoestetic Mandelic Acid peel 30% is applied immediately before the mask treatment at no extra cost. Mesoestetic Mandelic Acid is designed to target tough pigmentation and is strictly a doctors’ only product, this peel in combination with Dermamelan will deliver the best results.

What Is Dermamelan?
Dermamelan has similar active ingredients to Cosmelan but at 25 % higher concentration and the mask treatment and follow up must be done under strict supervision of a cosmetic doctor. Dermamelan treatment guarantees the improvement of skin blemishes with a very high safety margin. Dermamelan Depigmentation treatment’s principal action is the elimination of melanin patches on the face - melasma, also called chloasma if the pigmentation occurs with pregnancy. Dermamelan Depigmentation treatment involves a very versatile, dynamic process which is easily adapted to the needs of each individual patient.

How does Dermamelan Depigmentation work?
Dermamelan Depigmentation treatment action mechanism is based on the inhibition of tyrosinase, a basic enzyme in the melanin formation process. Several of the substances present in the Dermamelan formula act by blocking this enzyme, or even by inverting the metabolic process of the transformation chain. Melanogenesis comprises the following stages:

TYROSINE proceeds to DOPA by means of TYROSINASE.
DOPA proceeds to DOPAQUINONE by means of TYROSINASE.
DOPAQUINONE proceeds to PHAEOMELANINE and EUMELANIN by means of oxidation and cyclization.

What are the advantages of Dermamelan Depigmentation?
The Dermamelan Depigmentation treatment offers a series of major advantages and benefits compared with other types of depigmentation products found in the market:

• Very effective in all types of Melasma especially deep seated severe Melasma or post inflammatory hyperpigmentation PIH
  
• Effective for pigmentation that has failed to resolve after traditional skin lightening products
  
• Effective for pigmentation that has failed to resolve after traditional treatments such as superficial peels
  
• Rapid and easy depigmenting action
  
• Compatible with ALL skin types (Fitzpatrick I – VI)
  
• Light peeling effect
  
• Rejuvenates the skin
  
• Treatment can be used all year round
  
• Beneficial for acne patients
  
• Does not contain Hydroquinone or TCA
  
• High safety margin
  

What results can be expected from a Dermamelan Depigmentation treatment?
In 99% of the cases, the disappearance of the blemishes improves by 95%...
ONE WEEK after starting the Dermamelan Depigmentation treatment, a noticeable significant improvement of the skin is observed! The reduction of the treated blemish is detected and the appearance of new luminous and rejuvenated skin is present. At the end of the Dermamelan Depigmentation treatment, the blemishes start to disappear altogether, so that, although the patient may be able to “locate” the place where the spot was, the truth is that the pigmentation will have disappeared and nobody will be able to see it just by looking at it

What conditions can be treated with Dermamelan Depigmentation?
Dermamelan works by blocking the process that causes hyperpigmentation. It works for:

• Melasma
  
• Brown Spots
  
• Blotchy Skin
  
• Hyperpigmentation post acne spots
  
• Post-inflammatory hyperpigmentation
  
• Prevention of hyperpigmentation post-laser and post-peel
  

What are the active ingredients in Dermamelan Depigmentation?
Dermamelan has similar active ingredients to Cosmelan but at 25 % higher concentration.
Dermamelan 1 – mask
Azelaic Acid, Kojic Acid, Phytic Acid, Ascorbic Acid, Arbutine, and Titanium Dioxide
Dermamelan 2 – Maintenance Cream (30g)
Titanium Dioxide, Kojic Acid, Phytic Acid, Ascorbic Acid
Mesoestetic® Hydra Vital Factor K Cream (50ml)
Hydro nutritional cream for face and neck. Hydroviton, VItamin K, Vitamin E, Amniotic fluid, Glycerine, Silicone oil.

What precautions must be undertaken before proceeding with Dermamelan?
Please inform your cosmetic doctor if you have undergone any previous treatments, especially with glycolic acid. If confirmed, any treatment, especially Glycolic Acid, must be eliminated at least, one week prior to using Dermamelan Depigmentation treatment.

The Dermamelan Depigmentation treatment initiated at the medical office must be continued at home, on a daily basis, according to the guidelines indicated.

The treatment must not be interrupted under any circumstances, during the whole time prescribed.

It is completely forbidden to combine the Dermamelan Depigmentation treatment with other depigmentation treatments, as the appearance of undesired effects cannot be guaranteed.

Treatment control visits are recommended. 8 days after beginning of treatment, 15 days after, and a follow up visit every month thereafter.

What can be expected after a Dermamelan treatment mask?
First and second day
during the first two days of the treatment, the skin may turn red. If the skin is very sensitive, the patient may experience an itching feeling. Slight burning and tightening of the skin is also absolutely normal, especially during the first 24 to 48 hours after starting the treatment. To relieve these problems, it is advisable to apply the Mesoestetic® Hydra-vital factor K whenever necessary.

Reddening of the Skin that occurs on the face after applying the Mesoestetic® Dermamelan mask treatment; is similar to the effects of day-long exposure to the sun or the snow without sun protection (Intense reddening in skin type I and II and practically non existent in skin type IV and V).

Flaking may occur on all skin types (and more intensely in skin type I and II) between the second and third day. In this case it is advisable to apply the Mesoestetic® Hydra-vital factor K cream, repeating this every two hours on the day when the flaking is most intense repeating this every 2 hours until it improves. Do not pull on the flakes. Do not rub or scratch the skin. If necessary flakes can be cut off. Do not use exfoliants, scrubs or peels. Avoid steam baths, saunas and swimming in a hot spring for 2 weeks following treatment. It is advisable to wait until the initial flaking period is over before starting to apply make-up again.

Warning
If a severe skin reaction results from treatment do not proceed with maintenance treatment. Similarly, if scab formation is seen or if the skin is accidentally injured during the treatment period it is advisable to interrupt application of maintenance treatment. Use only Hydra-vital factor K and Sunscreen until the skin has settled and then again proceed with the maintenance treatment schedule. If in doubt, please contact your doctor at Clínica Privé immediately.

Third and fourth day
After the third or fourth day, the skin appears healthy and luminous and the marks begin to fade.

What can be expected after the home application of Dermamelan 2?
HOME TREATMENT – Dermamelan Maintenance Cream

The second phase of the Dermamelan consist of a home maintenance cream Dermamelan with the intention of securing the depigmentation by association of agents such as Kojic Acid, Phytic Acid, and Vitamin C. We have added a physical agent to block the sun and guarantee that the UV rays do not keep on aggravating unwanted skin hyperpigmentation.
This Dermamelan maintenance cream should be applied using the 3: 2: 1 principle.

• 3 times per day during the first month
  
• 2 times a day for 2 months
  
• 1 times a day for a prolonged period (up to a year if the pigmentation has been present for more than 2 years without treatment) see stabilization phase. This secures the obtained results guaranteeing an optimum depigmentation response.
  

What does the stabilization period of a Dermamelan depigmentation treatment mean?
The period following the initial 6 month treatment process, is called the STABILISATION period, and this can ideally be extended up to one year. Every effort should be made to continue treatment throughout the first summer. Even if the treatment is a great success, long term success depends on how well the protocol is followed, during both the treatment and stabilization phases. VERY GOOD sunblock is essential at all times.

What are the complimentary products that can be used with Dermamelan ?
Mesoestetic Vitamin C ampoules: use twice weekly before applying the Cosmelan 2 cream.
Hydra Vital K: The recommended moisturizer.
Regenerance Active: recommended moisturiser for sensitive skin.
Mesoestetic Complete sunblock: Highly recommended for continuous use.
Melanogel Touch: this can be applied on heavy spots. Recommended for added benefit.
Melanogel Touch anti-spot cream: this depigmentation cream works very well to maintain results during stabilization period.

What are important instructions before using Dermamelan ?
IMPORTANT NOTE: The treatment results are largely dependent on your cooperation and adherence to the post treatment skin care! The first 4 months constitute the treatment period. The period following is called the stabilisation period, and this is ideally extended up to one year, or longer. Every effort should be made to continue treatment throughout the first summer. Even if the depigmentation treatment was a great success, you need to understand that long term success depends on how well the protocol is followed, during both the treatment and stabilization phases. Avoid sun exposure for 2 weeks prior to treatment.

Can Dermamelan be combined with other treatments?
No peels can be done 2 weeks prior to treatment
No Laser treatment can be done on area to be treated 2 days prior to peel
Avoid Botox and Filler in area to be treated 2 weeks prior to peel